Protein name:
Thrombopoietin ;
Alternative:
Megakaryocyte colony-stimulating factor ;C-mpl ligand (ML) ;Myeloproliferative leukemia virus oncogene ligand ;Megakaryocyte growth and development factor (MGDF) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Subcellular Location:
Secreted
Protein Attributes:
50:
MELTDLLLAA | MLLAVARLTL | SSPVAPACDP | RLLNKLLRDS | HLLHSRLSQC |
100:
PDVDPLSIPV | LLPAVDFSLG | EWKTQTEQSK | AQDILGAVSL | LLEGVMAARG |
150:
QLEPSCLSSL | LGQLSGQVRL | LLGALQGLLG | TQLPLQGRTT | AHKDPNALFL |
200:
SLQQLLRGKV | RFLLLVEGPT | LCVRRTLPTT | AVPSSTSQLL | TLNKFPNRTS |
250:
GLLETNFSVT | ARTAGPGLLS | RLQGFRVKIT | PGQLNQTSRS | PVQISGYLNR |
300:
THGPVNGTHG | LFAGTSLQTL | EASDISPGAF | NKGSLAFNLQ | GGLPPSPSLA |
350:
PDGHTPFPPS | PALPTTHGSP | PQLHPLFPDP | STTMPNSTAP | HPVTMYPHPR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
Dog
Pig
ELISA Kit for Mouse Thrombopoietin
ELISA Kit for Mouse Thrombopoietin
ELISA Kit for Mouse Thrombopoietin
ELISA Kit for Mouse Thrombopoietin
ELISA Kit for Mouse Thrombopoietin
CLIA Kit for Mouse Thrombopoietin
CLIA Kit for Mouse Thrombopoietin
CLIA Kit for Mouse Thrombopoietin
CLIA Kit for Mouse Thrombopoietin
CLIA Kit for Mouse Thrombopoietin
Polyclonal Antibody for Mouse Thrombopoietin
Polyclonal Antibody for Mouse Thrombopoietin
Polyclonal Antibody for Mouse Thrombopoietin
Polyclonal Antibody for Mouse Thrombopoietin
Polyclonal Antibody for Mouse Thrombopoietin
Monoclonal Antibody for Mouse Thrombopoietin
Monoclonal Antibody for Mouse Thrombopoietin
Monoclonal Antibody for Mouse Thrombopoietin
Monoclonal Antibody for Mouse Thrombopoietin
Monoclonal Antibody for Mouse Thrombopoietin
Protein for Mouse Thrombopoietin
Protein for Mouse Thrombopoietin
Protein for Mouse Thrombopoietin
Protein for Mouse Thrombopoietin
Protein for Mouse Thrombopoietin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo."
Lok S.
,
Kaushansky K.
,
Holly R.D.
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Kuijper J.L.
,
Lofton-Day C.E.
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Oort P.J.
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Grant F.J.
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Heipel M.D.
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Kramer J.M.
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Bell L.A.N.
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Sprecher C.A.
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Blumberg H.
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Johnson R.
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Prunkard D.
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Ching A.F.T.
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Mathewes S.L.
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Bailey M.C.
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Forstrom J.W.
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Buddle M.M.
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Osborn S.G.
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Evans S.J.
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Sheppard P.O.
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Presnell S.R.
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O'Hara P.J.
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Hagen F.S.
,
Roth G.J.
,
Foster D.C.
more...
Nature369:565-568(1994)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Kidney .
2.
"Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl."
Bartley T.D.
,
Bogenberger J.
,
Hunt P.
,
Li Y.-S.
,
Lu H.S.
,
Martin F.
,
Chang M.-S.
,
Samal B.B.
,
Nichol J.L.
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Swift S.
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Johnson M.J.
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Hsu R.-Y.
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Parker V.P.
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Suggs S.
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Skrine J.D.
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Merewether L.A.
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Clogson C.
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Hsu E.
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Hokom M.M.
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Hornkohl A.
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Choi E.
,
Pangelinan M.
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Sun Y.
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Mar V.
,
McNich J.
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Simonet L.
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Jacobsen F.
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Xie C.
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Shutter J.
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Chute H.
,
Basu R.
,
Selander L.
,
Trollinger D.
,
Sieu L.
,
Padilla D.
,
Trail G.
,
Elliott G.
,
Izumi R.
,
Covey T.
,
Crouse J.
,
Garcia A.
,
Xu W.
,
del Castillo J.
,
Biron J.
,
Cole S.
,
Hu M.C.-T.
,
Pacifici R.
,
Ponting I.
,
Saris C.
,
Wen D.
,
Yung Y.P.
,
Lin H.
,
Bosselman R.A.
more...
Cell77:1117-1124(1994)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
FVB/N .
tissue :
Mammary gland .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION